The C-terminal residue of phage Vp16 PDF, the smallest peptide deformylase, acts as an offset element locking the active conformation

Prokaryotic proteins must be deformylated before the removal of their first methionine. Peptide deformylase (PDF) is indispensable and guarantees this mechanism. Recent metagenomics studies revealed new idiosyncratic PDF forms as the most abundant family of viral sequences. Little is known regarding...

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Bibliographic Details
Published in:Sci Rep
Main Authors: Grzela, Renata, Nusbaum, Julien, Fieulaine, Sonia, Lavecchia, Francesco, Bienvenut, Willy V., Dian, Cyril, Meinnel, Thierry, Giglione, Carmela
Format: Artigo
Language:Inglês
Published: Nature Publishing Group UK 2017
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5591237/
https://ncbi.nlm.nih.gov/pubmed/28887476
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-11329-3
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