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A unique peptide deformylase platform to rationally design and challenge novel active compounds
Peptide deformylase (PDF) is considered an excellent target to develop antibiotics. We have performed an extensive characterization of a new PDF from the pathogen Streptococcus agalactiae, showing properties similar to other known PDFs. S. agalactiae PDF could be used as PDF prototype as it allowed...
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| Опубликовано в: : | Sci Rep |
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| Главные авторы: | , , , , , , , , , , , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
Nature Publishing Group
2016
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5071857/ https://ncbi.nlm.nih.gov/pubmed/27762275 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep35429 |
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