CXCL12/CXCR4 pathway is activated by oncogenic JAK2 in a PI3K-dependent manner

JAK2 activation is the driver mechanism in BCR-ABL-negative myeloproliferative neoplasms (MPN). These diseases are characterized by an abnormal retention of hematopoietic stem cells within the bone marrow microenvironment and their increased trafficking to extramedullary sites. The CXCL12/CXCR4 axis...

Fuld beskrivelse

Na minha lista:
Bibliografiske detaljer
Udgivet i:Oncotarget
Main Authors: Abdelouahab, Hadjer, Zhang, Yanyan, Wittner, Monika, Oishi, Shinya, Fujii, Nobutaka, Besancenot, Rodolphe, Plo, Isabelle, Ribrag, Vincent, Solary, Eric, Vainchenker, William, Barosi, Giovanni, Louache, Fawzia
Format: Artigo
Sprog:Inglês
Udgivet: Impact Journals LLC 2016
Fag:
Research Paper
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5589564/
https://ncbi.nlm.nih.gov/pubmed/28903325
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.10789
Tags: Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!

Lignende værker