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Improving Gene Therapy Efficiency through the Enrichment of Human Hematopoietic Stem Cells
Lentiviral vector (LV)-based hematopoietic stem cell (HSC) gene therapy is becoming a promising clinical strategy for the treatment of genetic blood diseases. However, the current approach of modifying 1 × 10(8) to 1 × 10(9) CD34(+) cells per patient requires large amounts of LV, which is expensive...
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| Gepubliceerd in: | Mol Ther |
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| Hoofdauteurs: | , , , , , |
| Formaat: | Artigo |
| Taal: | Inglês |
| Gepubliceerd in: |
American Society of Gene & Cell Therapy
2017
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| Onderwerpen: | |
| Online toegang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5589063/ https://ncbi.nlm.nih.gov/pubmed/28663101 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ymthe.2017.05.023 |
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