טוען...
The human ankyrin 1 promoter insulator sustains gene expression in a β-globin lentiviral vector in hematopoietic stem cells
Lentiviral vectors designed for the treatment of the hemoglobinopathies require the inclusion of regulatory and strong enhancer elements to achieve sufficient expression of the β-globin transgene. Despite the inclusion of these elements, the efficacy of these vectors may be limited by transgene sile...
שמור ב:
| הוצא לאור ב: | Mol Ther Methods Clin Dev |
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| Main Authors: | , , , , , , , , , , , , |
| פורמט: | Artigo |
| שפה: | Inglês |
| יצא לאור: |
Nature Publishing Group
2015
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| נושאים: | |
| גישה מקוונת: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4445009/ https://ncbi.nlm.nih.gov/pubmed/26029723 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mtm.2015.12 |
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