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Alzheimer’s disease pathological lesions activate the spleen tyrosine kinase
The pathology of Alzheimer’s disease (AD) is characterized by dystrophic neurites (DNs) surrounding extracellular Aβ-plaques, microgliosis, astrogliosis, intraneuronal tau hyperphosphorylation and aggregation. We have previously shown that inhibition of the spleen tyrosine kinase (Syk) lowers Aβ pro...
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| Yayımlandı: | Acta Neuropathol Commun |
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| Asıl Yazarlar: | , , , , , , , |
| Materyal Türü: | Artigo |
| Dil: | Inglês |
| Baskı/Yayın Bilgisi: |
BioMed Central
2017
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| Konular: | |
| Online Erişim: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5588676/ https://ncbi.nlm.nih.gov/pubmed/28877763 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s40478-017-0472-2 |
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