MMP9 modulation improves specific neurobehavioral deficits in a mouse model of Alzheimer’s disease

BACKGROUND: Matrix metallopeptidase 9 (MMP9) has been implicated in a variety of neurological disorders, including Alzheimer’s disease (AD), where MMP9 levels are elevated in the brain and cerebrovasculature. Previously our group demonstrated apolipoprotein E4 (apoE4) was less efficient in regulatin...

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Detalhes bibliográficos
Publicado no:BMC Neurosci
Main Authors: Ringland, Charis, Schweig, Jonas Elias, Eisenbaum, Maxwell, Paris, Daniel, Ait-Ghezala, Ghania, Mullan, Michael, Crawford, Fiona, Abdullah, Laila, Bachmeier, Corbin
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2021
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8152085/
https://ncbi.nlm.nih.gov/pubmed/34034683
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12868-021-00643-2
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