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Alzheimer’s disease pathological lesions activate the spleen tyrosine kinase
The pathology of Alzheimer’s disease (AD) is characterized by dystrophic neurites (DNs) surrounding extracellular Aβ-plaques, microgliosis, astrogliosis, intraneuronal tau hyperphosphorylation and aggregation. We have previously shown that inhibition of the spleen tyrosine kinase (Syk) lowers Aβ pro...
Uloženo v:
| Vydáno v: | Acta Neuropathol Commun |
|---|---|
| Hlavní autoři: | , , , , , , , |
| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
BioMed Central
2017
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5588676/ https://ncbi.nlm.nih.gov/pubmed/28877763 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s40478-017-0472-2 |
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