Chronic Anatabine Treatment Reduces Alzheimer’s Disease (AD)-Like Pathology and Improves Socio-Behavioral Deficits in a Transgenic Mouse Model of AD

Anatabine is a minor tobacco alkaloid, which is also found in plants of the Solanaceae family and displays a chemical structure similarity with nicotine. We have shown previously that anatabine displays some anti-inflammatory properties and reduces microgliosis and tau phosphorylation in a pure mous...

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Veröffentlicht in:PLoS One
Hauptverfasser: Verma, Megha, Beaulieu-Abdelahad, David, Ait-Ghezala, Ghania, Li, Rena, Crawford, Fiona, Mullan, Michael, Paris, Daniel
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2015
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4444019/
https://ncbi.nlm.nih.gov/pubmed/26010758
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0128224
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