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Reduction of β-amyloid pathology by celastrol in a transgenic mouse model of Alzheimer's disease
BACKGROUND: Aβ deposits represent a neuropathological hallmark of Alzheimer's disease (AD). Both soluble and insoluble Aβ species are considered to be responsible for initiating the pathological cascade that eventually leads to AD. Therefore, the identification of therapeutic approaches that ca...
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| Main Authors: | , , , , , , , , |
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| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
BioMed Central
2010
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2841120/ https://ncbi.nlm.nih.gov/pubmed/20211007 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1742-2094-7-17 |
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