Reduction of β-amyloid pathology by celastrol in a transgenic mouse model of Alzheimer's disease

BACKGROUND: Aβ deposits represent a neuropathological hallmark of Alzheimer's disease (AD). Both soluble and insoluble Aβ species are considered to be responsible for initiating the pathological cascade that eventually leads to AD. Therefore, the identification of therapeutic approaches that ca...

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Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Paris, Daniel, Ganey, Nowell J, Laporte, Vincent, Patel, Nikunj S, Beaulieu-Abdelahad, David, Bachmeier, Corbin, March, Amelia, Ait-Ghezala, Ghania, Mullan, Michael J
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: BioMed Central 2010
Gaiak:
Research
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC2841120/
https://ncbi.nlm.nih.gov/pubmed/20211007
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1742-2094-7-17
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