Selective Antihypertensive Dihydropyridines Lower Aβ Accumulation by Targeting both the Production and the Clearance of Aβ across the Blood-Brain Barrier

Several large population-based or clinical trial studies have suggested that certain dihydropyridine (DHP) L-type calcium channel blockers (CCBs) used for the treatment of hypertension may confer protection against the development of Alzheimer disease (AD). However, other studies with drugs of the s...

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Main Authors: Paris, Daniel, Bachmeier, Corbin, Patel, Nikunj, Quadros, Amita, Volmar, Claude-Henry, Laporte, Vincent, Ganey, Jim, Beaulieu-Abdelahad, David, Ait-Ghezala, Ghania, Crawford, Fiona, Mullan, Michael J
Format: Artigo
Language:Inglês
Published: ScholarOne 2011
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3060987/
https://ncbi.nlm.nih.gov/pubmed/21170472
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2119/molmed.2010.00180
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