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Selective Antihypertensive Dihydropyridines Lower Aβ Accumulation by Targeting both the Production and the Clearance of Aβ across the Blood-Brain Barrier

Several large population-based or clinical trial studies have suggested that certain dihydropyridine (DHP) L-type calcium channel blockers (CCBs) used for the treatment of hypertension may confer protection against the development of Alzheimer disease (AD). However, other studies with drugs of the s...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Paris, Daniel, Bachmeier, Corbin, Patel, Nikunj, Quadros, Amita, Volmar, Claude-Henry, Laporte, Vincent, Ganey, Jim, Beaulieu-Abdelahad, David, Ait-Ghezala, Ghania, Crawford, Fiona, Mullan, Michael J
Format: Artigo
Sprache:Inglês
Veröffentlicht: ScholarOne 2011
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3060987/
https://ncbi.nlm.nih.gov/pubmed/21170472
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2119/molmed.2010.00180
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