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Spleen tyrosine kinase (SYK) blocks autophagic Tau degradation in vitro and in vivo
Spleen tyrosine kinase (SYK) plays a major role in inflammation and in adaptive immune responses and could therefore contribute to the neuroinflammation observed in various neurodegenerative diseases. Indeed, previously we have reported that SYK also regulates β-amyloid (Aβ) production and hyperphos...
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| Vydáno v: | J Biol Chem |
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| Hlavní autoři: | , , , , , , |
| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
American Society for Biochemistry and Molecular Biology
2019
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6737214/ https://ncbi.nlm.nih.gov/pubmed/31324720 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA119.008033 |
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