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Spleen tyrosine kinase (SYK) blocks autophagic Tau degradation in vitro and in vivo
Spleen tyrosine kinase (SYK) plays a major role in inflammation and in adaptive immune responses and could therefore contribute to the neuroinflammation observed in various neurodegenerative diseases. Indeed, previously we have reported that SYK also regulates β-amyloid (Aβ) production and hyperphos...
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| Veröffentlicht in: | J Biol Chem |
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| Hauptverfasser: | , , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
American Society for Biochemistry and Molecular Biology
2019
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6737214/ https://ncbi.nlm.nih.gov/pubmed/31324720 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA119.008033 |
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