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Influence of matrix metallopeptidase 9 on beta-amyloid elimination across the blood-brain barrier

Lipoprotein receptor transport across the blood-brain barrier (BBB) mediates beta-amyloid (Aβ) accumulation in the brain and may be a contributing factor in Alzheimer's disease (AD) pathogenesis. Lipoprotein receptors are susceptible to proteolytic shedding at the cell surface, which precludes...

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Bibliografiske detaljer
Udgivet i:Mol Neurobiol
Main Authors: Shackleton, Ben, Ringland, Charis, Abdullah, Laila, Mullan, Michael, Crawford, Fiona, Bachmeier, Corbin
Format: Artigo
Sprog:Inglês
Udgivet: 2019
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6842100/
https://ncbi.nlm.nih.gov/pubmed/31209784
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12035-019-01672-z
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