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Characterization and use of human brain microvascular endothelial cells to examine β-amyloid exchange in the blood-brain barrier
Alzheimer’s disease (AD) is characterized by excessive cerebrovascular deposition of the β-amyloid peptide (Aβ). The investigation of Aβ transport across the blood-brain barrier (BBB) has been hindered by inherent limitations in the cellular systems currently used to model the BBB, such as insuffici...
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Main Authors: | , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
Springer Netherlands
2010
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2995137/ https://ncbi.nlm.nih.gov/pubmed/20954006 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10616-010-9313-x |
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