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Characterization and use of human brain microvascular endothelial cells to examine β-amyloid exchange in the blood-brain barrier

Alzheimer’s disease (AD) is characterized by excessive cerebrovascular deposition of the β-amyloid peptide (Aβ). The investigation of Aβ transport across the blood-brain barrier (BBB) has been hindered by inherent limitations in the cellular systems currently used to model the BBB, such as insuffici...

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Détails bibliographiques
Auteurs principaux: Bachmeier, Corbin, Mullan, Michael, Paris, Daniel
Format: Artigo
Langue:Inglês
Publié: Springer Netherlands 2010
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2995137/
https://ncbi.nlm.nih.gov/pubmed/20954006
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10616-010-9313-x
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