Molecular Pathobiology of the Cerebrovasculature in Aging and in Alzheimers Disease Cases With Cerebral Amyloid Angiopathy

Cerebrovascular dysfunction and cerebral amyloid angiopathy (CAA) are hallmark features of Alzheimer's disease (AD). Molecular damage to cerebrovessels in AD may result in alterations in vascular clearance mechanisms leading to amyloid deposition around blood vessels and diminished neurovascula...

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Veröffentlicht in:Front Aging Neurosci
Hauptverfasser: Ojo, Joseph O., Reed, Jon M., Crynen, Gogce, Vallabhaneni, Prashanthi, Evans, James, Shackleton, Benjamin, Eisenbaum, Maximillian, Ringland, Charis, Edsell, Anastasia, Mullan, Michael, Crawford, Fiona, Bachmeier, Corbin
Format: Artigo
Sprache:Inglês
Veröffentlicht: Frontiers Media S.A. 2021
Schlagworte:
Neuroscience
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8166206/
https://ncbi.nlm.nih.gov/pubmed/34079449
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnagi.2021.658605
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