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Mural cell dysfunction leads to altered cerebrovascular tau uptake following repetitive head trauma

A pathological characteristic of repetitive traumatic brain injury (TBI) is the deposition of hyperphosphorylated and aggregated tau species in the brain and increased levels of extracellular monomeric tau are believed to play a role in the pathogenesis of neurodegenerative tauopathies. The pathways...

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Détails bibliographiques
Publié dans:Neurobiol Dis
Auteurs principaux: Ojo, Joseph, Eisenbaum, Max, Shackleton, Ben, Lynch, Cillian, Joshi, Utsav, Saltiel, Nicole, Pearson, Andrew, Ringland, Charis, Paris, Daniel, Mouzon, Benoit, Mullan, Michael, Crawford, Fiona, Bachmeier, Corbin
Format: Artigo
Langue:Inglês
Publié: 2020
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC8170787/
https://ncbi.nlm.nih.gov/pubmed/33383188
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.nbd.2020.105237
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