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Chronic Repetitive Mild Traumatic Brain Injury Results in Reduced Cerebral Blood Flow, Axonal Injury, Gliosis, and Increased T-Tau and Tau Oligomers

Exposure to repetitive mild traumatic brain injury (mTBI) is a risk factor for chronic traumatic encephalopathy, which is characterized by patchy deposition of hyperphosphorylated tau aggregates in neurons and astrocytes at the depths of cortical sulci. We developed an mTBI paradigm to explore effec...

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Bibliografske podrobnosti
izdano v:J Neuropathol Exp Neurol
Main Authors: Ojo, Joseph O., Mouzon, Benoit, Algamal, Moustafa, Leary, Paige, Lynch, Cillian, Abdullah, Laila, Evans, James, Mullan, Michael, Bachmeier, Corbin, Stewart, William, Crawford, Fiona
Format: Artigo
Jezik:Inglês
Izdano: Oxford University Press 2016
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4913432/
https://ncbi.nlm.nih.gov/pubmed/27251042
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/jnen/nlw035
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