Chronic Repetitive Mild Traumatic Brain Injury Results in Reduced Cerebral Blood Flow, Axonal Injury, Gliosis, and Increased T-Tau and Tau Oligomers

Exposure to repetitive mild traumatic brain injury (mTBI) is a risk factor for chronic traumatic encephalopathy, which is characterized by patchy deposition of hyperphosphorylated tau aggregates in neurons and astrocytes at the depths of cortical sulci. We developed an mTBI paradigm to explore effec...

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Bibliographic Details
Published in:J Neuropathol Exp Neurol
Main Authors: Ojo, Joseph O., Mouzon, Benoit, Algamal, Moustafa, Leary, Paige, Lynch, Cillian, Abdullah, Laila, Evans, James, Mullan, Michael, Bachmeier, Corbin, Stewart, William, Crawford, Fiona
Format: Artigo
Language:Inglês
Published: Oxford University Press 2016
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Original Articles
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4913432/
https://ncbi.nlm.nih.gov/pubmed/27251042
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/jnen/nlw035
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