ADA-07 suppresses solar ultraviolet-induced skin carcinogenesis by directly inhibiting TOPK

Cumulative exposure to solar ultraviolet (SUV) irradiation is regarded as the major etiologic factor in the development of skin cancer. The activation of the mitogen-activated protein kinase (MAPK) cascades occurs rapidly and is vital in the regulation of SUV-induced cellular responses. The T-LAK ce...

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Pubblicato in:Mol Cancer Ther
Autori principali: Gao, Ge, Zhang, Tianshun, Wang, Qiushi, Reddy, Kanamata, Chen, Hanyong, Yao, Ke, Wang, Keke, Roh, Eunmiri, Zykova, Tatyana, Ma, Weiya, Ryu, Joohyun, Curiel-Lewandrowski, Clara, Alberts, David, Dickinson, Sally E., Bode, Ann M., Xing, Ying, Dong, Zigang
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2017
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5587387/
https://ncbi.nlm.nih.gov/pubmed/28655782
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1535-7163.MCT-17-0212
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