ADA-07 suppresses solar ultraviolet-induced skin carcinogenesis by directly inhibiting TOPK

Cumulative exposure to solar ultraviolet (SUV) irradiation is regarded as the major etiologic factor in the development of skin cancer. The activation of the mitogen-activated protein kinase (MAPK) cascades occurs rapidly and is vital in the regulation of SUV-induced cellular responses. The T-LAK ce...

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Vydáno v:Mol Cancer Ther
Hlavní autoři: Gao, Ge, Zhang, Tianshun, Wang, Qiushi, Reddy, Kanamata, Chen, Hanyong, Yao, Ke, Wang, Keke, Roh, Eunmiri, Zykova, Tatyana, Ma, Weiya, Ryu, Joohyun, Curiel-Lewandrowski, Clara, Alberts, David, Dickinson, Sally E., Bode, Ann M., Xing, Ying, Dong, Zigang
Médium: Artigo
Jazyk:Inglês
Vydáno: 2017
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5587387/
https://ncbi.nlm.nih.gov/pubmed/28655782
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1535-7163.MCT-17-0212
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