ADA-07 suppresses solar ultraviolet-induced skin carcinogenesis by directly inhibiting TOPK

Cumulative exposure to solar ultraviolet (SUV) irradiation is regarded as the major etiologic factor in the development of skin cancer. The activation of the mitogen-activated protein kinase (MAPK) cascades occurs rapidly and is vital in the regulation of SUV-induced cellular responses. The T-LAK ce...

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Veröffentlicht in:Mol Cancer Ther
Hauptverfasser: Gao, Ge, Zhang, Tianshun, Wang, Qiushi, Reddy, Kanamata, Chen, Hanyong, Yao, Ke, Wang, Keke, Roh, Eunmiri, Zykova, Tatyana, Ma, Weiya, Ryu, Joohyun, Curiel-Lewandrowski, Clara, Alberts, David, Dickinson, Sally E., Bode, Ann M., Xing, Ying, Dong, Zigang
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2017
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5587387/
https://ncbi.nlm.nih.gov/pubmed/28655782
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1535-7163.MCT-17-0212
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