ADA-07 suppresses solar ultraviolet-induced skin carcinogenesis by directly inhibiting TOPK

Cumulative exposure to solar ultraviolet (SUV) irradiation is regarded as the major etiologic factor in the development of skin cancer. The activation of the mitogen-activated protein kinase (MAPK) cascades occurs rapidly and is vital in the regulation of SUV-induced cellular responses. The T-LAK ce...

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Detalhes bibliográficos
Publicado no:Mol Cancer Ther
Main Authors: Gao, Ge, Zhang, Tianshun, Wang, Qiushi, Reddy, Kanamata, Chen, Hanyong, Yao, Ke, Wang, Keke, Roh, Eunmiri, Zykova, Tatyana, Ma, Weiya, Ryu, Joohyun, Curiel-Lewandrowski, Clara, Alberts, David, Dickinson, Sally E., Bode, Ann M., Xing, Ying, Dong, Zigang
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5587387/
https://ncbi.nlm.nih.gov/pubmed/28655782
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1535-7163.MCT-17-0212
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