Structural insights into the interaction of the conserved mammalian proteins GAPR-1 and Beclin 1, a key autophagy protein

Mammalian Golgi-associated plant pathogenesis-related protein 1 (GAPR-1) is a negative autophagy regulator that binds Beclin 1, a key component of the autophagosome nucleation complex. Beclin 1 residues 267–284 are required for binding GAPR-1. Here, sequence analyses, structural modeling, mutagenesi...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Acta Crystallogr D Struct Biol
Egile Nagusiak: Li, Yue, Zhao, Yuting, Su, Minfei, Glover, Karen, Chakravarthy, Srinivas, Colbert, Christopher L., Levine, Beth, Sinha, Sangita C.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: International Union of Crystallography 2017
Gaiak:
Research Papers
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC5586249/
https://ncbi.nlm.nih.gov/pubmed/28876241
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1107/S2059798317011822
Etiketak: Etiketa erantsi
Etiketarik gabe, Izan zaitez lehena erregistro honi etiketa jartzen!

Antzeko izenburuak