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Conformational flexibility of BECN1: Essential to its key role in autophagy and beyond
BECN1 (Beclin 1), a highly conserved eukaryotic protein, is a key regulator of autophagy, a cellular homeostasis pathway, and also participates in vacuolar protein sorting, endocytic trafficking, and apoptosis. BECN1 is important for embryonic development, the innate immune response, tumor suppressi...
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| Published in: | Protein Sci |
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| Main Authors: | , , , |
| Format: | Artigo |
| Language: | Inglês |
| Published: |
John Wiley and Sons Inc.
2016
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5029530/ https://ncbi.nlm.nih.gov/pubmed/27414988 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/pro.2984 |
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