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Structural transitions in conserved, ordered Beclin 1 domains essential to regulating autophagy
Beclin 1 (BECN1) is a key regulator of autophagy, a critical catabolic homeostasis pathway that involves sequestration of selected cytoplasmic components by multilayered vesicles called autophagosomes, followed by lysosomal fusion and degradation. BECN1 is a core component of class III phosphatidyli...
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| Publicado no: | J Biol Chem |
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| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Biochemistry and Molecular Biology
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5625053/ https://ncbi.nlm.nih.gov/pubmed/28798234 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M117.804195 |
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