SIRT1 Enzymatically Potentiates 1,25-Dihydroxyvitamin D(3) Signaling via Vitamin D Receptor Deacetylation

The hormonal metabolite of vitamin D, 1,25-dihydroxyvitamin D(3) (1,25D), binds to the vitamin D receptor (VDR) and promotes heterodimerization of VDR with a retinoid-X-receptor (RXR) to genomically regulate diverse cellular processes. Herein, it is revealed for the first time that VDR is post-trans...

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Bibliografiske detaljer
Udgivet i:J Steroid Biochem Mol Biol
Main Authors: Sabir, Marya S., Khan, Zainab, Hu, Chengcheng, Galligan, Michael A., Dussik, Christopher M., Mallick, Sanchita, Stone, Angelika Dampf, Batie, Shane F., Jacobs, Elizabeth T., Whitfield, G. Kerr, Haussler, Mark R., Heck, Michael C., Jurutka, Peter W.
Format: Artigo
Sprog:Inglês
Udgivet: 2017
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5584940/
https://ncbi.nlm.nih.gov/pubmed/28636886
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jsbmb.2017.06.010
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