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Vitamin D Receptor Mediates a Myriad of Biological Actions Dependent on Its 1,25‐Dihydroxyvitamin D Ligand: Distinct Regulatory Themes Revealed by Induction of Klotho and Fibroblast Growth Factor‐23
The hormonal vitamin D metabolite, 1,25‐dihydroxyvitamin D [1,25(OH)(2)D], produced in kidney, acts in numerous end organs via the nuclear vitamin D receptor (VDR) to trigger molecular events that orchestrate bone mineral homeostasis. VDR is a ligand‐controlled transcription factor that obligatorily...
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| Udgivet i: | JBMR Plus |
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| Main Authors: | , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
John Wiley & Sons, Inc.
2020
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7839824/ https://ncbi.nlm.nih.gov/pubmed/33553988 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jbm4.10432 |
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