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1,25-Dihydroxyvitamin D(3) Regulation of Fibroblast Growth Factor-23 Expression in Bone Cells: Evidence for Primary and Secondary Mechanisms Modulated by Leptin and Interleukin-6
Fibroblast growth factor-23 (FGF23) is a circulating hormone that acts to correct hyperphosphatemic states by inhibiting renal phosphate reabsorption and to prevent hypervitaminosis D by feedback repressing 1, 25-dihydroxyvitamin D(3) (1,25(OH)(2)D(3)) biosynthesis. FGF23 gene expression in the oste...
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| Main Authors: | , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3595337/ https://ncbi.nlm.nih.gov/pubmed/23263654 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00223-012-9683-5 |
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