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The Role of Vitamin D in the FGF23, Klotho, and Phosphate Bone-Kidney Endocrine Axis

1,25-dihydroxyvitamin D (1,25D), through association with the nuclear vitamin D receptor (VDR), exerts control over a novel endocrine axis consisting of the bone-derived hormone FGF23, and the kidney-expressed klotho, CYP27B1, and CYP24A1 genes, which together prevent hyperphosphatemia/ectopic calci...

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Detalhes bibliográficos
Main Authors: Haussler, Mark R., Whitfield, G. Kerr, Kaneko, Ichiro, Forster, Ryan, Saini, Rimpi, Hsieh, Jui-Cheng, Haussler, Carol A., Jurutka, Peter W.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3288475/
https://ncbi.nlm.nih.gov/pubmed/21932165
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11154-011-9199-8
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