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The Role of Vitamin D in the FGF23, Klotho, and Phosphate Bone-Kidney Endocrine Axis
1,25-dihydroxyvitamin D (1,25D), through association with the nuclear vitamin D receptor (VDR), exerts control over a novel endocrine axis consisting of the bone-derived hormone FGF23, and the kidney-expressed klotho, CYP27B1, and CYP24A1 genes, which together prevent hyperphosphatemia/ectopic calci...
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| Main Authors: | , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
2012
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3288475/ https://ncbi.nlm.nih.gov/pubmed/21932165 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11154-011-9199-8 |
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