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Vitamin D Receptor Controls Expression of the Anti-aging Klotho Gene in Mouse and Human Renal Cells

Isoforms of the mammalian klotho protein serve as membrane co-receptors that regulate renal phosphate and calcium reabsorption. Phosphaturic effects of klotho are mediated in cooperation with fibroblast growth factor receptor-1 and its FGF23 ligand. The vitamin D receptor and its 1,25-dihydroxyvitam...

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Detalhes bibliográficos
Main Authors: Forster, Ryan E., Jurutka, Peter W., Hsieh, Jui-Cheng, Haussler, Carol A., Lowmiller, Christine L., Kaneko, Ichiro, Haussler, Mark R., Whitfield, G. Kerr
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3209523/
https://ncbi.nlm.nih.gov/pubmed/21982773
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbrc.2011.09.117
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