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The nuclear vitamin D receptor controls the expression of genes encoding factors which feed the “Fountain of Youth” to mediate healthful aging
The nuclear vitamin D receptor (VDR) binds 1,25-dihydroxyvitamin D(3) (1,25D), its high affinity renal endocrine ligand, to signal intestinal calcium and phosphate absorption plus bone remodeling, generating a mineralized skeleton free of rickets/osteomalacia with a reduced risk of osteoporotic frac...
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| Main Authors: | , , , , , , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
2010
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2906618/ https://ncbi.nlm.nih.gov/pubmed/20227497 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jsbmb.2010.03.019 |
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