SIRT1 Enzymatically Potentiates 1,25-Dihydroxyvitamin D(3) Signaling via Vitamin D Receptor Deacetylation

The hormonal metabolite of vitamin D, 1,25-dihydroxyvitamin D(3) (1,25D), binds to the vitamin D receptor (VDR) and promotes heterodimerization of VDR with a retinoid-X-receptor (RXR) to genomically regulate diverse cellular processes. Herein, it is revealed for the first time that VDR is post-trans...

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Bibliografski detalji
Izdano u:J Steroid Biochem Mol Biol
Glavni autori: Sabir, Marya S., Khan, Zainab, Hu, Chengcheng, Galligan, Michael A., Dussik, Christopher M., Mallick, Sanchita, Stone, Angelika Dampf, Batie, Shane F., Jacobs, Elizabeth T., Whitfield, G. Kerr, Haussler, Mark R., Heck, Michael C., Jurutka, Peter W.
Format: Artigo
Jezik:Inglês
Izdano: 2017
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Article
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5584940/
https://ncbi.nlm.nih.gov/pubmed/28636886
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jsbmb.2017.06.010
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