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SIRT1 Enzymatically Potentiates 1,25-Dihydroxyvitamin D(3) Signaling via Vitamin D Receptor Deacetylation
The hormonal metabolite of vitamin D, 1,25-dihydroxyvitamin D(3) (1,25D), binds to the vitamin D receptor (VDR) and promotes heterodimerization of VDR with a retinoid-X-receptor (RXR) to genomically regulate diverse cellular processes. Herein, it is revealed for the first time that VDR is post-trans...
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| Publicado no: | J Steroid Biochem Mol Biol |
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| Main Authors: | , , , , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5584940/ https://ncbi.nlm.nih.gov/pubmed/28636886 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jsbmb.2017.06.010 |
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