BDNF-TrkB controls cocaine-induced dendritic spines in rodent nucleus accumbens dissociated from increases in addictive behaviors

Chronic cocaine use is associated with prominent morphological changes in nucleus accumbens shell (NACsh) neurons, including increases in dendritic spine density along with enhanced motivation for cocaine, but a functional relationship between these morphological and behavioral phenomena has not bee...

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Veröffentlicht in:Proc Natl Acad Sci U S A
Hauptverfasser: Anderson, Ethan M., Wissman, Anne Marie, Chemplanikal, Joyce, Buzin, Nicole, Guzman, Daniel, Larson, Erin B., Neve, Rachael L., Nestler, Eric J., Cowan, Christopher W., Self, David W.
Format: Artigo
Sprache:Inglês
Veröffentlicht: National Academy of Sciences 2017
Schlagworte:
Biological Sciences
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5584417/
https://ncbi.nlm.nih.gov/pubmed/28808012
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1702441114
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