BDNF-TrkB controls cocaine-induced dendritic spines in rodent nucleus accumbens dissociated from increases in addictive behaviors

Chronic cocaine use is associated with prominent morphological changes in nucleus accumbens shell (NACsh) neurons, including increases in dendritic spine density along with enhanced motivation for cocaine, but a functional relationship between these morphological and behavioral phenomena has not bee...

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Vydáno v:Proc Natl Acad Sci U S A
Hlavní autoři: Anderson, Ethan M., Wissman, Anne Marie, Chemplanikal, Joyce, Buzin, Nicole, Guzman, Daniel, Larson, Erin B., Neve, Rachael L., Nestler, Eric J., Cowan, Christopher W., Self, David W.
Médium: Artigo
Jazyk:Inglês
Vydáno: National Academy of Sciences 2017
Témata:
Biological Sciences
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5584417/
https://ncbi.nlm.nih.gov/pubmed/28808012
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1702441114
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