BDNF-TrkB controls cocaine-induced dendritic spines in rodent nucleus accumbens dissociated from increases in addictive behaviors

Chronic cocaine use is associated with prominent morphological changes in nucleus accumbens shell (NACsh) neurons, including increases in dendritic spine density along with enhanced motivation for cocaine, but a functional relationship between these morphological and behavioral phenomena has not bee...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Anderson, Ethan M., Wissman, Anne Marie, Chemplanikal, Joyce, Buzin, Nicole, Guzman, Daniel, Larson, Erin B., Neve, Rachael L., Nestler, Eric J., Cowan, Christopher W., Self, David W.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2017
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5584417/
https://ncbi.nlm.nih.gov/pubmed/28808012
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1702441114
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