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EXO1 suppresses double-strand break induced homologous recombination between diverged sequences in mammalian cells
DNA double-strand breaks (DSBs) can be repaired through several mechanisms, including homologous recombination (HR). While HR between identical sequences is robust in mammalian cells, HR between diverged sequences is suppressed by DNA mismatch-repair (MMR) components such as MSH2. Exonuclease I (EXO...
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| Publicado no: | DNA Repair (Amst) |
|---|---|
| Main Authors: | , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5584059/ https://ncbi.nlm.nih.gov/pubmed/28711786 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.dnarep.2017.07.003 |
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