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Repair of Double-Strand Breaks by Homologous Recombination in Mismatch Repair-Defective Mammalian Cells

Chromosomal double-strand breaks (DSBs) stimulate homologous recombination by several orders of magnitude in mammalian cells, including murine embryonic stem (ES) cells, but the efficiency of recombination decreases as the heterology between the repair substrates increases (B. Elliott, C. Richardson...

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Hlavní autoři: Elliott, Beth, Jasin, Maria
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology 2001
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC86898/
https://ncbi.nlm.nih.gov/pubmed/11283247
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.21.8.2671-2682.2001
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