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Repair of Double-Strand Breaks by Homologous Recombination in Mismatch Repair-Defective Mammalian Cells

Chromosomal double-strand breaks (DSBs) stimulate homologous recombination by several orders of magnitude in mammalian cells, including murine embryonic stem (ES) cells, but the efficiency of recombination decreases as the heterology between the repair substrates increases (B. Elliott, C. Richardson...

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Publicat a:Mol Cell Biol
Autors principals: Elliott, Beth, Jasin, Maria
Format: Artigo
Idioma:Inglês
Publicat: Taylor & Francis 2001
Matèries:
Accés en línia:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC86898/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11283247/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/MCB.21.8.2671-2682.2001
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