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Repair of Double-Strand Breaks by Homologous Recombination in Mismatch Repair-Defective Mammalian Cells

Chromosomal double-strand breaks (DSBs) stimulate homologous recombination by several orders of magnitude in mammalian cells, including murine embryonic stem (ES) cells, but the efficiency of recombination decreases as the heterology between the repair substrates increases (B. Elliott, C. Richardson...

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Sonraí Bibleagrafaíochta
Main Authors: Elliott, Beth, Jasin, Maria
Formáid: Artigo
Teanga:Inglês
Foilsithe: American Society for Microbiology 2001
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC86898/
https://ncbi.nlm.nih.gov/pubmed/11283247
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.21.8.2671-2682.2001
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