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Repair of Double-Strand Breaks by Homologous Recombination in Mismatch Repair-Defective Mammalian Cells

Chromosomal double-strand breaks (DSBs) stimulate homologous recombination by several orders of magnitude in mammalian cells, including murine embryonic stem (ES) cells, but the efficiency of recombination decreases as the heterology between the repair substrates increases (B. Elliott, C. Richardson...

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Vydáno v:Mol Cell Biol
Hlavní autoři: Elliott, Beth, Jasin, Maria
Médium: Artigo
Jazyk:Inglês
Vydáno: Taylor & Francis 2001
Témata:
On-line přístup:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC86898/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11283247/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/MCB.21.8.2671-2682.2001
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