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Role for the Mammalian Swi5-Sfr1 Complex in DNA Strand Break Repair through Homologous Recombination
In fission yeast, the Swi5-Sfr1 complex plays an important role in homologous recombination (HR), a pathway crucial for the maintenance of genomic integrity. Here we identify and characterize mammalian Swi5 and Sfr1 homologues. Mouse Swi5 and Sfr1 are nuclear proteins that form a complex in vivo and...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Public Library of Science
2010
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| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2954829/ https://ncbi.nlm.nih.gov/pubmed/20976249 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1001160 |
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