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Homology-directed repair is a major double-strand break repair pathway in mammalian cells

Mammalian cells have been presumed to repair potentially lethal chromosomal double-strand breaks (DSBs) in large part by processes that do not require homology to the break site. This contrasts with Saccharomyces cerevisiae where the major DSB repair pathway is homologous recombination. Recently, it...

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Detalhes bibliográficos
Main Authors: Liang, Feng, Han, Mingguang, Romanienko, Peter J., Jasin, Maria
Formato: Artigo
Idioma:Inglês
Publicado em: The National Academy of Sciences 1998
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC20233/
https://ncbi.nlm.nih.gov/pubmed/9560248
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