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Homology-directed repair is a major double-strand break repair pathway in mammalian cells

Mammalian cells have been presumed to repair potentially lethal chromosomal double-strand breaks (DSBs) in large part by processes that do not require homology to the break site. This contrasts with Saccharomyces cerevisiae where the major DSB repair pathway is homologous recombination. Recently, it...

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Publicat a:Proc Natl Acad Sci U S A
Autors principals: Liang, Feng, Han, Mingguang, Romanienko, Peter J., Jasin, Maria
Format: Artigo
Idioma:Inglês
Publicat: National Academy of Sciences 1998
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Accés en línia:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC20233/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9560248/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.95.9.5172
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