scid mutation in mice confers hypersensitivity to ionizing radiation and a deficiency in DNA double-strand break repair.

C.B-17 severe combined immunodeficient (scid) mice carry the scid mutation and are severely deficient in both T cell- and B cell-mediated immunity, apparently as a result of defective V(D)J joining of the immunoglobulin and T-cell receptor gene elements. In the present studies, we have defined the t...

Полное описание

Библиографические подробности

Опубликовано в::	Proc Natl Acad Sci U S A
Главные авторы:	Biedermann, K A, Sun, J R, Giaccia, A J, Tosto, L M, Brown, J M
Формат:	Artigo
Язык:	Inglês
Опубликовано:	National Academy of Sciences 1991
Предметы:	Research Article
Online-ссылка:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC51024/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1996340/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.88.4.1394
Метки:	Добавить метку Нет меток, Требуется 1-ая метка записи!