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Homology-directed repair is a major double-strand break repair pathway in mammalian cells

Mammalian cells have been presumed to repair potentially lethal chromosomal double-strand breaks (DSBs) in large part by processes that do not require homology to the break site. This contrasts with Saccharomyces cerevisiae where the major DSB repair pathway is homologous recombination. Recently, it...

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Bibliografiske detaljer
Main Authors: Liang, Feng, Han, Mingguang, Romanienko, Peter J., Jasin, Maria
Format: Artigo
Sprog:Inglês
Udgivet: The National Academy of Sciences 1998
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC20233/
https://ncbi.nlm.nih.gov/pubmed/9560248
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