An xrcc4 defect or Wortmannin stimulates homologous recombination specifically induced by double-strand breaks in mammalian cells

Non-homologous end joining (NHEJ) and homologous recombination (HR) are two alternative/competitor pathways for the repair of DNA double-strand breaks (DSBs). To gain further insights into the regulation of DSB repair, we detail here the different HR pathways affected by (i) the inactivation of DNA-...

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Detalhes bibliográficos

Publicado no:	Nucleic Acids Res
Principais autores:	Delacôte, Fabien, Han, Mingguang, Stamato, Thomas D., Jasin, Maria, Lopez, Bernard S.
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Oxford University Press 2002
Assuntos:	Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC137076/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12140331/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/gkf452
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