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An xrcc4 defect or Wortmannin stimulates homologous recombination specifically induced by double-strand breaks in mammalian cells

Non-homologous end joining (NHEJ) and homologous recombination (HR) are two alternative/competitor pathways for the repair of DNA double-strand breaks (DSBs). To gain further insights into the regulation of DSB repair, we detail here the different HR pathways affected by (i) the inactivation of DNA-...

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Detalhes bibliográficos
Main Authors: Delacôte, Fabien, Han, Mingguang, Stamato, Thomas D., Jasin, Maria, Lopez, Bernard S.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2002
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC137076/
https://ncbi.nlm.nih.gov/pubmed/12140331
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