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Mechanisms of Recombination between Diverged Sequences in Wild-Type and BLM-Deficient Mouse and Human Cells

Double-strand breaks (DSBs) are particularly deleterious DNA lesions for which cells have developed multiple mechanisms of repair. One major mechanism of DSB repair in mammalian cells is homologous recombination (HR), whereby a homologous donor sequence is used as a template for repair. For this rea...

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Detalhes bibliográficos
Main Authors: LaRocque, Jeannine R., Jasin, Maria
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2849462/
https://ncbi.nlm.nih.gov/pubmed/20154148
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.01553-09
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