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Mechanisms of Recombination between Diverged Sequences in Wild-Type and BLM-Deficient Mouse and Human Cells

Double-strand breaks (DSBs) are particularly deleterious DNA lesions for which cells have developed multiple mechanisms of repair. One major mechanism of DSB repair in mammalian cells is homologous recombination (HR), whereby a homologous donor sequence is used as a template for repair. For this rea...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: LaRocque, Jeannine R., Jasin, Maria
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology (ASM) 2010
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2849462/
https://ncbi.nlm.nih.gov/pubmed/20154148
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.01553-09
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