GABA(A) receptor α(4)-subunit knockout enhances lung inflammation and airway reactivity in a murine asthma model

Emerging evidence indicates that hypnotic anesthetics affect immune function. Many anesthetics potentiate γ-aminobutyric acid A receptor (GABA(A)R) activation, and these receptors are expressed on multiple subtypes of immune cells, providing a potential mechanistic link. Like immune cells, airway sm...

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Detalhes bibliográficos
Publicado no:Am J Physiol Lung Cell Mol Physiol
Main Authors: Yocum, Gene T., Turner, Damian L., Danielsson, Jennifer, Barajas, Matthew B., Zhang, Yi, Xu, Dingbang, Harrison, Neil L., Homanics, Gregg E., Farber, Donna L., Emala, Charles W.
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2017
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5582940/
https://ncbi.nlm.nih.gov/pubmed/28473323
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajplung.00107.2017
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