Targeting the restricted α-subunit repertoire of airway smooth muscle GABA(A) receptors augments airway smooth muscle relaxation

The prevalence of asthma has taken on pandemic proportions. Since this disease predisposes patients to severe acute airway constriction, novel mechanisms capable of promoting airway smooth muscle relaxation would be clinically valuable. We have recently demonstrated that activation of endogenous air...

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Autores principales: Gallos, George, Yim, Peter, Chang, Sucie, Zhang, Yi, Xu, Dingbang, Cook, James M., Gerthoffer, William T., Emala, Charles W.
Formato: Artigo
Lenguaje:Inglês
Publicado: American Physiological Society 2012
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Articles
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3349365/
https://ncbi.nlm.nih.gov/pubmed/21949156
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajplung.00131.2011
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